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KMID : 0438520120190020053
Journal of the Korean Society of Neonatology
2012 Volume.19 No. 2 p.53 ~ p.64
Antimicrobial Management of Neonatal Sepsis
Kim Ai-Rhan

Abstract
Neonatal infections are frequent complications of neonates receiving intensive care unit. In particular, large cohort study has suggested that neonatal infections among extremely low birth weight infants are associated with poor neurodevelopmental and growth outcomes in early childhood. This review article will focus on the rational use of empirical antibiotics/antifungal therapy for early and late onset sepsis/fungemia, duration of antibiotic treatment, highlight clinically relevant aspects of the antibiotics commonly used in the treatment of sepsis, antibiotics requiring therapeutic dose monitoring, and management of antibiotic-resistant infection in the neonate.
KEYWORD
Neonate, Sepsis, Antibiotics, Therapeutic drug monitoring, Resistance
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